Metrohm – NIRS XDS – MasterLab Analyzer
The NIRS XDS MasterLab Analyzer enables the rapid, nondestructive analyses of solid-state dosage forms such as tablets, capsules, film-coated tablets, gel tablets and gel capsules for manufacturers in the pharmaceuticals industry. Solids in vials can also be analyzed with the NIRS XDS MasterLab Analyzer. The analysis takes place in reflection or transmission mode. The sample input proceeds via a sample slide that can be moved in x and y direction and that is designed for trays with several tablets and/or vials. Analyses of individual samples are optimized with an iris. An optionally available coarse granular sample cell for coarse granular substances extends analysis to include practically all solid forms ranging from fine powders to coarse granular materials, e.g., pellets and flakes
Technical Specifications
| Measuring mode | Reflection and transmission |
| Sample interface | Direct analysis |
|---|---|
| Reflection | 400–2,500 nm |
| Transmission | 800–1,650 nm |
| Measuring module | Hot-swappable |
| Detectors | Reflection Silicon (400–1,100 nm), lead sulfide (1,100–2,500 nm) |
| Transmission InGaAs (indium gallium arsenide) | 800–1,650 nm |
| Data collection speed | 2 scans/s |
| Data point interval | 0.5 nm |
| Wavelength accuracy (currently recognized standard) | Reflection < 0.05 nm (SRM 1920) Transmission < 0.05 nm (Metrohm NIRS wavelength standards) |
| Wavelength precision 1 | < 0.005 nm |
| Wavelength precision 2 (instrument to instrument) | < 0.020 nm |
| Stray light | < 0.1% at 2,300 nm |
| Photometric linearity | < 1% of the measured value |
| Bandpass | Reflection 8.75 ±0.10 nm Transmission 9.50 ±0.10 nm |
| Noise (RMS): Reflection | 400–700 nm < 50 micro AU 700–2,500 nm < 20 micro AU |
| Noise (RMS): Transmission | 850–1,100 nm < 30 micro AU 1,100–1,600 nm < 20 micro AU |
| Weight | 39.0 kg (86.0 lbs) |
| Dimensions (W × H × D) | 380 × 346 × 559 mm (15″ × 13.6″ × 22″) |
| Operating temperature range | 4.5–35°C (40–95°F) |
| Relative humidity | 10–90% RH, non-condensing |
Key Features
NIRS XDS MasterLab Analyzer
- Reflection and transmission analyses in one instrument
- Sample slide for xy positioning of trays with multiple tablets or vials, iris for individual samples, optional coarse granular sample cell for coarse granular substances
- Optimal sample analysis by adapting the measuring spot to the diameter of the sample vials or tablets
- Universal interface for quickly changing the measuring modules in just seconds
- Network-compatible – central result and data management (client-server solution)
NIRSystems XDS Analyzers – Pharmaceutical Testing
Key Industries
- Chemical
- Cosmetics & Personal Care
- Oil & Gas
- Pharmaceutical
- Polymers, Plastics and Rubbers
- Powders & Pigments / Coating
Brand
Founded in 1943 by the engineer Bertold Suhner, Metrohm is one of the world’s leading maker of instruments for chemical analysis. Metrohm is unique in offering solutions for all varieties of ion analysis. Besides the above, the Metrohm product lines also include a complete portfolio for NIR-/ and Raman spectroscopy, software, dosing systems and solutions for laboratory automation. Metrohm is owned 100% by the Swiss Metrohm foundation and is represented in more than 120 countries by its own subsidiaries or exclusive distributors, respectively. Customers are supported with unparalleled application know-how and service.