Zetasizer Advance is the successor to the highly successful and market-leading Zetasizer Nano.

Each of the three models in the Zetasizer Advance Range offers particle size, particle charge (zeta potential) and molecular weight analysis. In addition, each benefits from advances including Adaptive Correlation, M3-PALS zeta potential analysis, constant current zeta mode and our deep learning-based data quality advice system.

Each of the three models is available as a Blue Label or Red Label variant:

• Choose Blue Label for routine sample investigation such as metallic colloids, metal oxides and pigments
• Choose Red Label for more challenging sample types, such as proteins, surfactant solutions and low solid content samples

All Zetasizer Advance systems offer on-site upgradeability with minimal downtime. Should your needs change, your Zetasizer can adapt to new challenges.

Raman spectroscopy can be used for direct sample analysis typically without preprocessing or preparation. Raman has the unique capability of being able to test a sample directly through transparent packing material like glass or plastic, making it a fast, easy method that can be used for material identification and analysis wherever it is needed. With their portability and intuitive operation, handheld Raman spectrometers considerably increase efficiency by eliminating the need for additional space and wet chemistry.

The Metrohm Instant Raman Analyzer (MIRA) DS is a ruggedized, high-performance, handheld Raman spectrometer used for rapid, nondestructive determination of illicit materials, e.g. drugs, explosives, starting materials, and hazardous agents. Despite the small size of the instrument, Mira DS is extremely rugged and features a high-efficiency spectrograph equipped with our unique Orbital-Raster-Scan (ORS) technology. The Advanced package includes the Library of illicit materials, calibration standard, universal attachment for analyses in bottles or bags or for direct analysis, and the right-angle attachment, ideal for running samples on a surface and/or in a bag. Class 3B operation.

Mira DS Flex package allows the user to customize the Mira DS to meet their needs. The Flex package includes the basic components needed to operate the Mira DS without sampling attachments. At least one sampling attachment is required for operation. The Mira DS Flex package includes the library of illicit materials, a calibration standard, USB cable and laser safety goggles. Class 3B operation.

The Metrohm Instant Raman Analyzer (MIRA) P is a high-performance, handheld Raman spectrometer used for rapid, nondestructive determination and verification of different material types, such as Pharmaceutical APIs and excipients. Despite the small size of the instrument, the Mira P has a ruggedized design and features a high-efficiency spectrograph design equipped with our unique Orbital-Raster-Scan (ORS) technology. The Mira P is fully compliant with FDA 21 CFR Part 11 regulations.

The Advanced Package includes an attachment lens for analyzing materials directly or through containers (laser class 3b), as well as a vial holder attachment for analyzing samples contained in glass vials (laser class 1).

The Mira P Flex package allows users to customize Mira P to meet their needs. The Flex package includes the basic components needed to operate the Mira P without sampling attachments. At least one sampling attachment is required for operation. The Mira P Flex package includes the USP library, calibration/verification accessories, USB cable and laser safety goggles. Class 3B operation.

Metrohm Instant SERS Analyzer (Misa) is a high performance, portable analyzer system used for rapid, trace level detection / identification of illicit materials, food additives and food contaminants. Misa features a high-efficiency spectrograph equipped with Metrohm’s unique Orbital-Raster-Scan (ORS) technology. It has a minimal footprint and extended battery life, perfect for on-site testing or mobile laboratory applications. Misa offers various Laser Class 1 attachments for flexible sampling options. Analyzer operation is available through BlueTooth or USB connectivity.

The Misa Basic package allows users to customize Misa to suit their needs. It is a starter package that contains the basic components for performing SERS analyses using Metrohm’s nanoparticle solutions.

The Misa Basic package includes the Misa instrument, a Misa Vial Attachment, a USB Mini Cable, a USB Power Supply and Misa Cal software for operating the instrument.

The NanoLIBS® LIBS analyzer is a state-of-the-art, handheld instrument for laser-induced breakdown spectroscopy used in rapid identification of solid materials based on elemental analysis. The NanoLIBS provides considerable time savings in materials identification and confirmation, improving compliance with raw material testing directives while at the same time increasing productivity. The NanoLIBS is lightweight with a high-brightness touch screen for rapid material identification, giving results in seconds. NanoLIBS ID data management stores data in a secure database on a PC and/or server, enabling e-signatures on reports, report generation, as well as methods and account management.

The NanoRam is a state-of-the-art, handheld Raman instrument for nondestructive identification and verification of incoming raw materials such as APIs, excipients, and intermediates. Compact and flexible, the NanoRam can be used by non-technical users to rapidly identify samples in the warehouse, on the loading dock, or in the lab, minimizing quarantine areas and expediting materials through the manufacturing lifecycle. Utilizing Raman technology, nondestructive analysis can be performed through transparent containers, maintaining the volume and integrity of the sample.

The NanoRam-1064 is a state-of-the-art handheld Raman instrument for nondestructive identification and verification of incoming raw materials such as APIs, excipients, and intermediates. Compact and agile, the NanoRam can be used by non-technical users to rapidly identify samples in the lab, warehouse, loading dock or field, helping to eliminate quarantine areas and expedite materials through the manufacturing lifecycle. Utilizing Raman technology, analysis can be performed through transparent containers, all while maintaining the volume and integrity of the sample. The high-performance NanoRam-1064 minimizes fluorescence, and can differentiate different grades of cellulose, polysorbate and Opadry®.

The NIRS DS2500 Analyzer is the tried and tested, flexible solution for routine analysis of solids, creams, and optionally also liquids along the entire production chain. Its robust design makes the NIRS DS2500 Analyzer resistant to dust, moisture, vibrations, and temperature fluctuations, which means that it is eminently suited for use in harsh production environments. The NIRS DS2500 covers the full spectral range from 400 to 2500 nm and delivers accurate, reproducible results in under a minute. The NIRS DS2500 Analyzer meets the demands of the pharmaceutical industry and supports users in their day-to-day tasks thanks to its simple operation.

The NIRS XDS Interactance OptiProbe Analyzer enables the simple and reliable monitoring of chemical reactions in technical centers and pilot plants. The method development and the scale-up of production processes are areas of application in which the NIRS XDS Interactance OptiProbe Analyzer supplies precise results regarding the identity and quality of a wide variety of samples. Whereas solids, strongly scattering liquids and slurries are measured with the reflection probe, the immersion probe is used to analyze aqueous products, clear liquids and solvents. The probe is connected to the analyzer through an optical fiber to enable secure measurements even under rough and/or dangerous conditions in the processing environment.

The NIRS XDS MasterLab Analyzer enables the rapid, nondestructive analyses of solid-state dosage forms such as tablets, capsules, film-coated tablets, gel tablets and gel capsules for manufacturers in the pharmaceuticals industry. Solids in vials can also be analyzed with the NIRS XDS MasterLab Analyzer. The analysis takes place in reflection or transmission mode. The sample input proceeds via a sample slide that can be moved in x and y direction and that is designed for trays with several tablets and/or vials. Analyses of individual samples are optimized with an iris. An optionally available coarse granular sample cell for coarse granular substances extends analysis to include practically all solid forms ranging from fine powders to coarse granular materials, e.g., pellets and flakes

The NIRS XDS RapidContent Analyzer enables rapid, nondestructive analyses of solid powders, coarser granulates, pellets or flakes. Composition or material identification testing is performed either in the laboratory or at-line, on samples contained in their original packaging, bags or vials. An optional variable spot-size feature enables the sample illumination to be adjusted based on the physical properties of your samples.

The NIRS XDS RapidLiquid Analyzer enables rapid, precise analyses of liquid formulations and substances. Precise measurement results at the push of a button make the NIRS XDS RapidLiquid Analyzer an equally reliable and simple solution for quality monitoring in laboratories and processes. The samples are transferred to quartz cuvettes designed for multiple use or disposable glass vials; a tempered sample compartment ensures reproducible analysis conditions and thus accurate measurement results